MyBioSource.com's RNASE1 Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The RNASE1 Antibody (N-term) was generated using RNase A, RNASE1, and RNS1 as the antigen and it reacts with Human.
Description
This gene encodes a member of the pancreatic-type of
secretory ribonucleases, a subset of the ribonuclease A
superfamily. The encoded endonuclease cleaves internal
phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It
prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic
nucleotides, with a pH optimum near 8.0. The encoded protein is
monomeric and more commonly acts to degrade ds-RNA over ss-RNA.
Alternative splicing occurs at this locus and four transcript
variants encoding the same protein have been identified. [provided
by RefSeq]